Around 31% of Adults in the United States are affected by some sort of Anxiety Disorder, making it the most prominent health condition in the United States today. CBD, or cannabidiol helps regulate fear and anxiety induced behaviors by binding to cannabinoid receptors in our brain. In fact, research suggests that CBD can help treat a variety of anxiety disorders, including Generalized Anxiety Disorder, Post Traumatic Stress Disorder, Panic Disorder, Obsessive-compulsive Disorder, and Social Anxiety Disorder.

Research Surrounding CBD

CBD interact with the body’s Endocannabinoid System. The Endocannabinoid System, or ECS, is responsible for regulating different process in the body (Sleep, Stress, Anxiety, Depression, Appetite, Reproduction and more!) and ensures that the body maintains homeostasis. Homeostasis is  the bodies tendency to maintain a relatively stable internal equilibrium regardless of outside influences. The ECS is made up of three part; Endocannabinoids, Receptors, and Enzymes.

Cannabinoids have a similar structure to Endocannabinoids that are produced naturally in the body.  This allows them to bind to CB1, and CB2 receptors located throughout our body, thus eliciting a normal physiological response.  The effects vary depending on the ratio of cannabinoids ingested and the specific receptors to which they bind.

The euphoric and medicinal effects you experience from cannabinoids like THC and CBD are produced when they interact with the body’s Endocannabinoid System.

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For example, THC (Marijuana) binds to the CB1 receptors within the ECS, thus eliciting the “High” sensation. The metabolic enzymes that would normally degrade the cannabinoid aren’t as effective on THC then they are on natural endocannabinoids like anandamide, resulting in a longer lasting calming effect after THC use.

CBD ultimately disrupts the ECS natural processes,  thus eliciting a long lasting calming effect throughout the body which is beneficial for individuals suffering from anxiety disorders, chronic pain, depression, or loss of appetite. For more information on the details associated with the ECS and CBD, check out Ace Drop’s CBD and ECS page!

Current Research

The way CBD interacts with the CB1 receptors in the brain isn’t fully understood.

There is some research that suggests CBD affect how your brain’s chemical receptors respond to the serotonin that’s already in your system. Serotonin, a neurotransmitter, is a chemical in your body that plays a role in regulating your mood, sleep, digestion, and behavior.

Low serotonin levels are commonly associated with people who have depression, and in some cases low serotonin levels are also associated with those suffering from anxiety.

Research suggests the Serotonin levels can help treat certain ailments like anxiety and depression. A 2014 animal study found that CBD’s effect on these ECS receptors in the brain produced both antidepressant and anti-anxiety effects.  With the right dosage, CBD can help in curbing anxiety symptoms on top of relieving aches.

Other research illustrates CBD’s process to disrupt ECS’ natural processes. Cannabidiol has shown to block the enzyme, FAAH, which is responsible for breaking down anandamide.  This allows for a surplus of anandamide in the body, thus eliciting a longer lasting calming effect for the individual.  Basically, CBD has shown to block the FAAH enzyme from breaking down anandamide, resulting in endocannabinoids having more effect on the body, which can be beneficial for people who are dealing with anxiety disorders, as well as pain, nausea, and numerous other conditions.

2020 study conducted in New Zealand monitored 397 adults while on a strict CBD concentration regiment.  The participants were taking CBD to treat a variety of ailments, including non-cancer pain, cancer related symptoms, neurological symptoms and mental health symptoms.

All participants in the group reported improvements in their overall quality of life after a 3-week CBD trail period.  The individuals who received CBD treatment for anxiety or depression reportedly experienced improvements in their ability to perform daily functions and reduce pain and anxiety or depression symptoms.  70% of study participants reported some level of satisfaction with CBD treatment, ranging from good to excellent.

Interested in more CBD related content? Check out Ace Drop’s “CBD and MS” page!